PJNMed |

Case Report

Volume: 13 | Issue: 1 | Published: Mar 24, 2023 | Pages: 31 - 36 | DOI: 10.24911/PJNMed.175-1658810334

Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients

Authors: Azra Parveen , Arzoo Fatima Saleem , Ahmad Qureshy , Abubaker Shahid

Article Info

Authors

Azra Parveen

Department of Nuclear Medicine, INMOL Cancer Hospital, Lahore, Pakistan

Arzoo Fatima Saleem

Department of Nuclear Medicine, INMOL Cancer Hospital, Lahore, Pakistan

Ahmad Qureshy

DG sciences, PAES Head office, Islamabad, Pakistan

Abubaker Shahid

Department of Nuclear Medicine & Oncology, INMOL Cancer Hospital, Lahore, Pakistan.

Publication History

Received: July 26, 2022

Accepted: January 17, 2023

Published: March 24, 2023

Abstract

Background: Bone scintigraphy with 99mTc-labelled diphosphonates can identify prostate cancer (PCa) bone metastases with high sensitivity but relatively low specificity. Single photon emission computed tomography /computed tomography (SPECT/CT) can add value to the planar bone scintigraphy in the detection of bone metastases. Case presentation: We present a diagnosed case of Prostatic Adenocarcinoma of a 62 year old male patient who underwent 99mTc-Methyldiphosphonate (MDP) planar bone scintigraphy followed by SPECT/CT as a part of staging algorithm. Planar bone imaging showed homogeneous and symmetrical tracer uptake throughout the visualized skeleton. As the patient had complaints of urinary obstruction and severe backache: so, the sacrum could not be adequately assessed on planar bone imaging; therefore SPECT/CT of lumbar spine and pelvic region was performed. His regional SPECT-CT study of the lumbar and pelvic region, revealed widespread diffuse tracer avid osteoblastic lesions throughout the visualized lower lumbar spine, sacrum, pelvis and proximal femori, suggestive of skeletal metastases. Conclusion: We conclude that SPECT/CT scintigraphy has a diagnostic edge over planar bone imaging in detecting bone metastases in prostate cancer patients.

Keywords: SPECT/CT, Planar bone scan, Prostate cancer, Prostate specific antigen, equivocal lesions, case report

Pubmed Style

Azra Parveen, Arzoo Fatima Saleem, Ahmad Qureshy, Abubaker Shahid. Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. PJN Med. 2023; 24 (March 2023): 31-36. doi:10.24911/PJNMed.175-1658810334

Web Style

Azra Parveen, Arzoo Fatima Saleem, Ahmad Qureshy, Abubaker Shahid. Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. https://www.pjnmed.epublisyst.com/articles/2042 [Access: November 08, 2025]. doi:10.24911/PJNMed.175-1658810334

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Azra Parveen, Arzoo Fatima Saleem, Ahmad Qureshy, Abubaker Shahid. Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. PJN Med. (2023), [cited November 08, 2025]; 24 (March 2023): 31-36. doi:10.24911/PJNMed.175-1658810334

Harvard Style

Azra Parveen, Arzoo Fatima Saleem, Ahmad Qureshy, Abubaker Shahid (2023) Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. PJN Med, 24 (March 2023): 31-36. doi:10.24911/PJNMed.175-1658810334

Chicago Style

Azra Parveen, Arzoo Fatima Saleem, Ahmad Qureshy, Abubaker Shahid. "Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients." 24 (2023), 31-36. doi:10.24911/PJNMed.175-1658810334

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Azra Parveen, Arzoo Fatima Saleem, Ahmad Qureshy, Abubaker Shahid (2023) Diagnostic edge of SPECT/CT scintigraphy over planar bone imaging for detection of bone metastases in prostate cancer patients. , 24 (March 2023), 31-36. doi:10.24911/PJNMed.175-1658810334